7W5Z
Cryo-EM structure of Tetrahymena thermophila mitochondrial complex IV, composite dimer model
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, GB (U1, u1) | Unknown peptide | polymer | 98 | 8358.3 | 2 | Tetrahymena thermophila | ||
| 2 | B, HB (U2, u2) | Transmembrane protein, putative | polymer | 3634 | 417001.6 | 2 | UniProt (Q22C06) | Tetrahymena thermophila | |
| 3 | C, IB (U3, u3) | Unknown peptide | polymer | 34 | 2911.6 | 2 | Tetrahymena thermophila | ||
| 4 | D, JB (U4, u4) | Unknown peptide | polymer | 30 | 2571.2 | 2 | Tetrahymena thermophila | ||
| 5 | E, KB (U5, u5) | Uncharacterized protein | polymer | 172 | 20909.6 | 2 | UniProt (Q23FE4) Pfam (PF14536) | Tetrahymena thermophila | |
| 6 | F, LB (U6, u6) | Protein transporter Sec61 alpha subunit | polymer | 478 | 53674.3 | 2 | UniProt (W7XHC8) Pfam (PF10559) Pfam (PF00344) | Tetrahymena thermophila | |
| 7 | G, MB (C1, c1) | Cytochrome c oxidase subunit 1 | polymer | 688 | 80564.9 | 2 | UniProt (Q950Y4) | Tetrahymena thermophila | |
| 8 | H, NB (C2, c2) | Cytochrome c oxidase subunit 2 | polymer | 604 | 72388.9 | 2 | UniProt (Q950Y9) | Tetrahymena thermophila | |
| 9 | I, OB (C3, c3) | Ymf68 | polymer | 594 | 72782.5 | 2 | UniProt (Q950Y6) | Tetrahymena thermophila | |
| 10 | J, PB (5B, 5b) | Cytochrome C oxidase subunit Vb protein | polymer | 637 | 75431.3 | 2 | UniProt (Q23FF5) Pfam (PF01215) | Tetrahymena thermophila | |
| 11 | K, QB (6A, 6a) | Transmembrane protein, putative | polymer | 130 | 15618.3 | 2 | UniProt (W7XCY5) | Tetrahymena thermophila | |
| 12 | L, RB (6B, 6b) | Cytochrome c oxidase subunit 6B | polymer | 230 | 27946.4 | 2 | UniProt (Q24I72) | Tetrahymena thermophila | |
| 13 | M, SB (6L, 6l) | Cytochrome c oxidase subunit 6B-like | polymer | 88 | 10228.7 | 2 | UniProt (I7LVX0) | Tetrahymena thermophila | |
| 14 | N, TB (6C, 6c) | Transmembrane protein, putative | polymer | 103 | 12786.3 | 2 | UniProt (Q23DS4) | Tetrahymena thermophila | |
| 15 | O, UB (7A, 7a) | Transmembrane protein, putative | polymer | 133 | 16413.6 | 2 | UniProt (I7MGF9) | Tetrahymena thermophila | |
| 16 | P, VB (7C, 7c) | Cytochrome c oxidase subunit 7C | polymer | 236 | 28746.6 | 2 | UniProt (W7X287) | Tetrahymena thermophila | |
| 17 | Q, WB (7L, 7l) | CTF/NF-I domain-containing protein | polymer | 990 | 116812.8 | 2 | UniProt (Q22CI1) | Tetrahymena thermophila | |
| 18 | R, XB (M1, m1) | Oxoglutarate/malate translocator protein, putative | polymer | 346 | 40392.2 | 2 | UniProt (A4VDV3) Pfam (PF00153) | Tetrahymena thermophila | |
| 19 | S, YB (M2, m2) | 2-oxoglutarate/malate carrier protein | polymer | 318 | 36118.3 | 2 | UniProt (Q23M99) Pfam (PF00153) | Tetrahymena thermophila | |
| 20 | T, ZB (M3, m3) | Carrier protein | polymer | 330 | 37095.1 | 2 | UniProt (Q22ZA6) Pfam (PF00153) | Tetrahymena thermophila | |
| 21 | AC, U (T1, t1) | Tim10/DDP family zinc finger protein | polymer | 72 | 8009.0 | 2 | UniProt (W7X3D6) Pfam (PF02953) | Tetrahymena thermophila | |
| 22 | BC, V (T2, t2) | Cytochrome c oxidase small TIM subunit 2 | polymer | 72 | 8354.6 | 2 | UniProt (W7XDM6) | Tetrahymena thermophila | |
| 23 | CC, W (T3, t3) | Cytochrome c oxidase small TIM subunit 3 | polymer | 93 | 10435.7 | 2 | UniProt (Q231A8) | Tetrahymena thermophila | |
| 24 | DC, X (T4, t4) | Cytochrome c oxidase small TIM subunit 4 | polymer | 68 | 8109.1 | 2 | UniProt (Q22A35) | Tetrahymena thermophila | |
| 25 | EC, Y (T5, t5) | Cytochrome c oxidase small TIM subunit 5 | polymer | 81 | 8965.9 | 2 | UniProt (Q22N23) | Tetrahymena thermophila | |
| 26 | FC, Z (T6, t6) | Cytochrome c oxidase small TIM subunit 6 | polymer | 72 | 8183.4 | 2 | UniProt (Q233U0) | Tetrahymena thermophila | |
| 27 | AA, GC (BP, bp) | Chromosome condensation regulator RCC1 repeat protein | polymer | 380 | 41202.6 | 2 | UniProt (Q22RF2) Pfam (PF00415) | Tetrahymena thermophila | |
| 28 | BA, HC (FS, fs) | Iron-binding zinc finger CDGSH type protein | polymer | 188 | 21476.9 | 2 | UniProt (I7M8P0) | Tetrahymena thermophila | |
| 29 | CA, IC (AC, ac) | Cytochrome c oxidase acyl carrier-like subunit | polymer | 127 | 14740.9 | 2 | UniProt (Q24C97) | Tetrahymena thermophila | |
| 30 | DA, JC (Y7, y7) | Ymf67 | polymer | 453 | 54538.5 | 2 | UniProt (Q950Y7) | Tetrahymena thermophila | |
| 31 | EA, KC (Y0, y0) | Ymf70 | polymer | 89 | 10919.9 | 2 | UniProt (Q950Y0) | Tetrahymena thermophila | |
| 32 | FA, LC (Y5, y5) | Ymf75 | polymer | 190 | 23325.8 | 2 | UniProt (Q951A7) | Tetrahymena thermophila | |
| 33 | GA, MC (A, a) | Transmembrane protein, putative | polymer | 490 | 57814.5 | 2 | UniProt (Q22PJ5) | Tetrahymena thermophila | |
| 34 | HA, NC (B, b) | Protein phosphatase 2C, putative | polymer | 473 | 53011.3 | 2 | UniProt (Q22FX8) | Tetrahymena thermophila | |
| 35 | IA, LD (C, c) | Cyclic nucleotide-binding domain protein | polymer | 1471 | 172272.8 | 2 | UniProt (A4VCQ2) Pfam (PF00520) Pfam (PF00027) Pfam (PF00098) | Tetrahymena thermophila | |
| 36 | JA, OC (D, d) | SURF1-like protein | polymer | 402 | 47088.0 | 2 | UniProt (I7M1Q4) Pfam (PF02104) | Tetrahymena thermophila | |
| 37 | KA, PC (E, e) | TraB family protein | polymer | 385 | 45050.9 | 2 | UniProt (Q23DP7) | Tetrahymena thermophila | |
| 38 | LA, QC (F, f) | Transmembrane protein, putative | polymer | 348 | 41307.4 | 2 | UniProt (Q23DG8) | Tetrahymena thermophila | |
| 39 | MA, RC (G, g) | Cytochrome c oxidase subunit TT7 | polymer | 318 | 37553.0 | 2 | UniProt (Q23DZ5) | Tetrahymena thermophila | |
| 40 | NA, SC (H, h) | SURF1-like protein | polymer | 318 | 35794.4 | 2 | UniProt (I7LTZ4) Pfam (PF02104) | Tetrahymena thermophila | |
| 41 | OA, TC (I, i) | Cytochrome c oxidase subunit TT9 | polymer | 252 | 29865.7 | 2 | UniProt (I7LY65) | Tetrahymena thermophila | |
| 42 | PA, UC (J, j) | Cytochrome c oxidase subunit TT10 | polymer | 234 | 28101.5 | 2 | UniProt (I7MD70) | Tetrahymena thermophila | |
| 43 | QA, VC (K, k) | Cytochrome c oxidase subunit TT11 | polymer | 231 | 27034.7 | 2 | UniProt (W7X4J9) | Tetrahymena thermophila | |
| 44 | RA, WC (L, l) | Cytochrome c oxidase subunit TT12 | polymer | 222 | 26738.4 | 2 | UniProt (I7M3P9) | Tetrahymena thermophila | |
| 45 | SA, XC (M, m) | Transmembrane protein, putative | polymer | 220 | 26601.2 | 2 | UniProt (W7WZP1) | Tetrahymena thermophila | |
| 46 | TA, YC (N, n) | Transmembrane protein, putative | polymer | 210 | 24701.1 | 2 | UniProt (I7LZX8) | Tetrahymena thermophila | |
| 47 | UA, ZC (O, o) | Cytochrome c oxidase subunit TT15 | polymer | 193 | 23257.7 | 2 | UniProt (Q23F08) | Tetrahymena thermophila | |
| 48 | AD, VA (P, p) | Cytochrome c oxidase subunit TT16 | polymer | 175 | 20007.3 | 2 | UniProt (I7M8Y9) | Tetrahymena thermophila | |
| 49 | BD, WA (Q, q) | Transmembrane protein, putative | polymer | 173 | 20346.2 | 2 | UniProt (Q23D87) | Tetrahymena thermophila | |
| 50 | CD, XA (R, r) | Cytochrome c oxidase subunit TT18 | polymer | 173 | 20025.1 | 2 | UniProt (I7MKT6) | Tetrahymena thermophila | |
| 51 | DD, YA (S, s) | Cytochrome c oxidase subunit TT19 | polymer | 170 | 19882.8 | 2 | UniProt (Q230X6) | Tetrahymena thermophila | |
| 52 | ED, ZA (T, t) | Transmembrane protein, putative | polymer | 158 | 18801.6 | 2 | UniProt (Q23VY4) | Tetrahymena thermophila | |
| 53 | AB, FD (U, u) | Transmembrane protein, putative | polymer | 154 | 18600.4 | 2 | UniProt (Q22DP8) | Tetrahymena thermophila | |
| 54 | BB, GD (V, v) | Cytochrome c oxidase subunit TT22 | polymer | 149 | 17701.1 | 2 | UniProt (I7MFV5) | Tetrahymena thermophila | |
| 55 | CB, HD (W, w) | Transmembrane protein, putative | polymer | 124 | 15588.6 | 2 | UniProt (Q23TE5) | Tetrahymena thermophila | |
| 56 | DB, ID (X, x) | Transmembrane protein, putative | polymer | 122 | 14302.5 | 2 | UniProt (Q22W32) | Tetrahymena thermophila | |
| 57 | EB, JD (Y, y) | Cytochrome c oxidase subunit TT25 | polymer | 105 | 12273.9 | 2 | UniProt (I7M9E7) | Tetrahymena thermophila | |
| 58 | FB, KD (Z, z) | Cytochrome c oxidase subunit TT26 | polymer | 90 | 10418.7 | 2 | UniProt (I7LTF1) | Tetrahymena thermophila | |
| 59 | MD, ND, VF, WF (C1, c1) | HEME-A | non-polymer | 852.8 | 4 | Chemie (HEA) | |||
| 60 | CG, DG, OD, TD, UD... (c2, C1, C2, c1) | COPPER (II) ION | non-polymer | 63.5 | 6 | Chemie (CU) | |||
| 61 | PD, YF (C1, c1) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 62 | AH, BH, CF, DF, DI... (m2, A, v, c3, 7C...) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 34 | Chemie (PC1) | |||
| 63 | AF, AG, AI, BE, BF... (Y0, c1, t, 5B, Y5...) | CARDIOLIPIN | non-polymer | 1464.0 | 68 | Chemie (CDL) | |||
| 64 | AE, JG, MF, VH (5B, 5b, M, m) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 65 | FH, GH, XE, YE (fs, FS) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 4 | Chemie (FES) |
Sequence modifications
BP, bp: 83 - 412 (UniProt: Q22RF2)
| PDB | External Database | Details |
|---|---|---|
| Glu 413 | - | expression tag |
| Thr 414 | - | expression tag |
| Gly 415 | - | expression tag |
| Lys 416 | - | expression tag |
| Ile 417 | - | expression tag |
| Tyr 418 | - | expression tag |
| Gln 419 | - | expression tag |
| Phe 420 | - | expression tag |
| Asn 421 | - | expression tag |
| Glu 422 | - | expression tag |
| Phe 423 | - | expression tag |
| Val 424 | - | expression tag |
| Gly 425 | - | expression tag |
| Val 426 | - | expression tag |
| Ser 427 | - | expression tag |
| Thr 428 | - | expression tag |
| Asn 429 | - | expression tag |
| Glu 430 | - | expression tag |
| Val 431 | - | expression tag |
| Gly 432 | - | expression tag |
| Asn 433 | - | expression tag |
| Asp 434 | - | expression tag |
| Tyr 435 | - | expression tag |
| Asn 436 | - | expression tag |
| Val 437 | - | expression tag |
| Ala 438 | - | expression tag |
| Asp 439 | - | expression tag |
| Ser 440 | - | expression tag |
| Lys 441 | - | expression tag |
| Ala 442 | - | expression tag |
| Phe 443 | - | expression tag |
| Glu 444 | - | expression tag |
| Gly 445 | - | expression tag |
| Lys 446 | - | expression tag |
| Val 447 | - | expression tag |
| Val 448 | - | expression tag |
| Asp 449 | - | expression tag |
| Leu 450 | - | expression tag |
| Gly 451 | - | expression tag |
| Gly 452 | - | expression tag |
| Ser 453 | - | expression tag |
| Tyr 454 | - | expression tag |
| Gly 455 | - | expression tag |
| Ile 456 | - | expression tag |
| Arg 457 | - | expression tag |
| Phe 458 | - | expression tag |
| Ala 459 | - | expression tag |
| Ile 460 | - | expression tag |
| Val 461 | - | expression tag |
| Asn 462 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 116 |
| Total formula weight | 4462311.4 | |
| Non-Polymers* | Number of molecules | 122 |
| Total formula weight | 131226.0 | |
| All* | Total formula weight | 4593537.4 |
