7W5R

KRAS G12V and peptide complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I, M, Q...	Isoform 2B of GTPase KRas	polymer	174	20013.5	6	UniProt (P01116-2) Pfam (PF00071) UniProt (by SIFTS) (P01116) In PDB	Homo sapiens (human)	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2	H, X	LEU-TYR-ASP-VAL-ALA	polymer	5	579.6	2		Homo sapiens
3	A, E, I, M, Q...	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4	A, E, I, M, Q...	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	6	Chemie (GDP)

Sequence modifications

A, E, I, M, Q, U: 1 - 168 (UniProt: P01116-2)

PDB	External Database	Details
Val 12	Gly 12	engineered mutation
His 169	-	expression tag
His 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	121240.5
Non-Polymers*	Number of molecules	12
	Total formula weight	2805.0
All*	Total formula weight	124045.6

*Water molecules are not included.