7W5R
KRAS G12V and peptide complex
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003924 | molecular_function | GTPase activity |
A | 0005525 | molecular_function | GTP binding |
A | 0007165 | biological_process | signal transduction |
A | 0016020 | cellular_component | membrane |
E | 0003924 | molecular_function | GTPase activity |
E | 0005525 | molecular_function | GTP binding |
E | 0007165 | biological_process | signal transduction |
E | 0016020 | cellular_component | membrane |
I | 0003924 | molecular_function | GTPase activity |
I | 0005525 | molecular_function | GTP binding |
I | 0007165 | biological_process | signal transduction |
I | 0016020 | cellular_component | membrane |
M | 0003924 | molecular_function | GTPase activity |
M | 0005525 | molecular_function | GTP binding |
M | 0007165 | biological_process | signal transduction |
M | 0016020 | cellular_component | membrane |
Q | 0003924 | molecular_function | GTPase activity |
Q | 0005525 | molecular_function | GTP binding |
Q | 0007165 | biological_process | signal transduction |
Q | 0016020 | cellular_component | membrane |
U | 0003924 | molecular_function | GTPase activity |
U | 0005525 | molecular_function | GTP binding |
U | 0007165 | biological_process | signal transduction |
U | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 24 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22431598, ECO:0000269|PubMed:22566140 |
Chain | Residue | Details |
A | GLY10 | |
I | VAL29 | |
I | ALA59 | |
I | ASN116 | |
M | GLY10 | |
M | VAL29 | |
M | ALA59 | |
M | ASN116 | |
Q | GLY10 | |
Q | VAL29 | |
Q | ALA59 | |
A | VAL29 | |
Q | ASN116 | |
U | GLY10 | |
U | VAL29 | |
U | ALA59 | |
U | ASN116 | |
A | ALA59 | |
A | ASN116 | |
E | GLY10 | |
E | VAL29 | |
E | ALA59 | |
E | ASN116 | |
I | GLY10 |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | MOD_RES: N-acetylmethionine; in GTPase KRas; alternate => ECO:0000269|Ref.17 |
Chain | Residue | Details |
A | MET1 | |
E | MET1 | |
I | MET1 | |
M | MET1 | |
Q | MET1 | |
U | MET1 |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | MOD_RES: N-acetylthreonine; in GTPase KRas, N-terminally processed => ECO:0000269|Ref.17 |
Chain | Residue | Details |
A | THR2 | |
E | THR2 | |
I | THR2 | |
M | THR2 | |
Q | THR2 | |
U | THR2 |
site_id | SWS_FT_FI4 |
Number of Residues | 6 |
Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:22711838 |
Chain | Residue | Details |
A | LYS104 | |
E | LYS104 | |
I | LYS104 | |
M | LYS104 | |
Q | LYS104 | |
U | LYS104 |
site_id | SWS_FT_FI5 |
Number of Residues | 6 |
Details | CARBOHYD: (Microbial infection) O-linked (Glc) threonine; by P.sordellii toxin TcsL => ECO:0000269|PubMed:19744486 |
Chain | Residue | Details |
A | THR35 | |
E | THR35 | |
I | THR35 | |
M | THR35 | |
Q | THR35 | |
U | THR35 |