7W4Y
Crystal structure of PDE4D catalytic domain complexed with 33a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 373 | 42789.1 | 2 | UniProt (Q08499) Pfam (PF00233) In PDB | Homo sapiens (human) | DPDE3,PDE43 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | A, B | (2R,4S)-6-ethyl-2-(2-hydroxyethyl)-2,8-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-c][1,8]naphthyridin-5-one | non-polymer | 356.5 | 2 | Chemie (8GO) | |||
| 5 | water | water | 18.0 | 480 | Chemie (HOH) |
Sequence modifications
A, B: 78 - 449 (UniProt: Q08499)
| PDB | External Database | Details |
|---|---|---|
| Ala 450 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85578.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 892.3 | |
| All* | Total formula weight | 86470.5 |
