7W0D
Dicer2-LoqsPD-dsRNA complex at mid-translocation state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (B, G) | Loquacious, isoform D | polymer | 359 | 38502.6 | 2 | UniProt (M9MRT5) Pfam (PF00035) UniProt (by SIFTS) (Q9VJY9) | Drosophila melanogaster (Fruit fly) | |
| 2 | B, F (D, C) | dsRNA | polymer | 52 | 16646.9 | 2 | Drosophila melanogaster | ||
| 3 | D, E (A, F) | Dicer-2, isoform A | polymer | 1722 | 198006.7 | 2 | UniProt (A1ZAW0) Pfam (PF00270) Pfam (PF00271) Pfam (PF03368) Pfam (PF20931) Pfam (PF02170) Pfam (PF00636) Pfam (PF00035) | Drosophila melanogaster (Fruit fly) | FI15132p1 |
| 4 | G, I (A, F) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | H, J (A, F) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) |
Sequence modifications
A, F: 1 - 1722 (UniProt: A1ZAW0)
| PDB | External Database | Details |
|---|---|---|
| Asn 1217 | Asp 1217 | engineered mutation |
| Asn 1476 | Asp 1476 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 506312.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 903.0 | |
| All* | Total formula weight | 507215.3 |
