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7VV4

Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with linear cortistatin-14, local

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(R)
Mas-related G-protein coupled receptor member X2polymer33037124.01UniProt (Q96LB1)
Pfam (PF00001)
Homo sapiens (Human)
2B
(L)
circular cortistatin-14polymer141726.01UniProt (O00230)
Pfam (PF03002)
Homo sapiens
3C
(R)
CHOLESTEROLnon-polymer386.71Chemie (CLR)
Sequence modifications
L: 21 - 34 (UniProt: O00230)
PDBExternal DatabaseDetails
Lys 23Arg 94conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight38850.0
Non-Polymers*Number of molecules1
Total formula weight386.7
All*Total formula weight39236.7
*Water molecules are not included.

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PDB entries from 2024-12-18

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