7VTC
Crystal structure of MERS main protease in complex with PF07321332
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 3C-like proteinase | polymer | 322 | 35235.2 | 2 | UniProt (T2B9A8) Pfam (PF05409) UniProt (by SIFTS) (K9N7C7) In PDB | Middle East respiratory syndrome-related coronavirus (MERS-CoV) | |
2 | A | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide | non-polymer | 501.5 | 1 | Chemie (4WI) | |||
3 | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 301 (UniProt: T2B9A8)
PDB | External Database | Details |
---|---|---|
Ser 1 | - | expression tag |
Gly 2 | - | expression tag |
Ile 302 | - | expression tag |
Leu 303 | - | expression tag |
Gly 304 | - | expression tag |
Ser 305 | - | expression tag |
Thr 306 | - | expression tag |
Met 307 | - | expression tag |
Leu 308 | - | expression tag |
Glu 309 | - | expression tag |
Asp 310 | - | expression tag |
Glu 311 | - | expression tag |
Phe 312 | - | expression tag |
Thr 313 | - | expression tag |
Pro 314 | - | expression tag |
Glu 315 | - | expression tag |
Asp 316 | - | expression tag |
Val 317 | - | expression tag |
Asn 318 | - | expression tag |
Met 319 | - | expression tag |
Gln 320 | - | expression tag |
Ile 321 | - | expression tag |
Met 322 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70470.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 501.5 | |
All* | Total formula weight | 70972.0 |