7VR7
Inward-facing structure of human EAAT2 in the WAY213613-bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Excitatory amino acid transporter 2 | polymer | 581 | 63016.9 | 1 | UniProt (P43004) Pfam (PF00375) | Homo sapiens (human) | Glutamate/aspartate transporter II,Sodium-dependent glutamate/aspartate transporter 2,Solute carrier family 1 member 2 |
| 2 | B (A) | (2S)-2-azanyl-4-[[4-[2-bromanyl-4,5-bis(fluoranyl)phenoxy]phenyl]amino]-4-oxidanylidene-butanoic acid | non-polymer | 415.2 | 1 | Chemie (GJ0) | |||
| 3 | C (A) | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en | non-polymer | 544.8 | 1 | Chemie (9Z9) | |||
| 4 | D, E (A) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) | |||
| 5 | F, G (A) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 2 | Chemie (PC1) |
Sequence modifications
A: 1 - 574 (UniProt: P43004)
| PDB | External Database | Details |
|---|---|---|
| Glu 575 | - | expression tag |
| Asn 576 | - | expression tag |
| Leu 577 | - | expression tag |
| Tyr 578 | - | expression tag |
| Phe 579 | - | expression tag |
| Gln 580 | - | expression tag |
| Gly 581 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 63016.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3313.6 | |
| All* | Total formula weight | 66330.5 |
