7VQT
Crystal structure of LSD1 in complex with compound 5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific histone demethylase 1A | polymer | 669 | 74333.0 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) | Homo sapiens (Human) | BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2 |
| 2 | B, C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 3 | F (A) | L(+)-TARTARIC ACID | non-polymer | 150.1 | 1 | Chemie (TLA) | |||
| 4 | G (A) | 3-[3,5-bis(fluoranyl)-2-[(2-fluoranylpyridin-4-yl)methoxy]phenyl]propanal | non-polymer | 295.3 | 1 | Chemie (7UW) | |||
| 5 | H (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) |
Sequence modifications
A: 172 - 833 (UniProt: O60341)
| PDB | External Database | Details |
|---|---|---|
| Gly 165 | - | expression tag |
| Pro 166 | - | expression tag |
| Leu 167 | - | expression tag |
| Gly 168 | - | expression tag |
| Ser 169 | - | expression tag |
| His 170 | - | expression tag |
| Met 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 74333.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1599.3 | |
| All* | Total formula weight | 75932.3 |
