7VOX

The crystal structure of human forkhead box protein A in complex with DNA 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (D, F)	DNA (5'-D(P*TP*CP*GP*AP*TP*AP*AP*TP*AP*AP*AP*TP*AP*TP*TP*T)-3')	polymer	16	4895.2	2		Homo sapiens
2	B, D (E, G)	DNA (5'-D(P*AP*AP*AP*TP*AP*TP*TP*TP*AP*TP*TP*AP*TP*CP*GP*A)-3')	polymer	16	4895.2	2		Homo sapiens
3	E, F, G, H (A, B, C, H)	Hepatocyte nuclear factor 3-alpha	polymer	102	11924.6	4	UniProt (P55317) Pfam (PF00250)	Homo sapiens (Human)	HNF-3-alpha,HNF-3A,Forkhead box protein A1,Transcription factor 3A,TCF-3A
4	I, J (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	K, L, M, N, O... (D, E, F, G, A...)	water	water		18.0	446	Chemie (HOH)

Sequence modifications

A, B, C, H: 168 - 264 (UniProt: P55317)

PDB	External Database	Details
Gly 163	-	expression tag
Ala 164	-	expression tag
Met 165	-	expression tag
Gly 166	-	expression tag
Ser 167	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	67279.4
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	67328.0

*Water molecules are not included.