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7VN9

Crystal structure of human coronavirus 229E spike protein receptor-binding domain in complex with C04 Fab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(H, A)
C04 Fab heavy chainpolymer23124304.12Homo sapiens (human)
2B, E
(L, B)
C04 Fab light chainpolymer21523343.92Homo sapiens (human)
3C, F
(E, C)
Spike glycoprotein S1polymer14816194.32UniProt (P15423)
Pfam (PF01600)
Human coronavirus 229E (HCoV-229E)S glycoprotein,E2,Peplomer protein
4G, I
(D, G)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.52In PDB
GlyTouCan (G15407YE)
5H
(F)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
6J
(C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
Sequence modifications
E, C: 294 - 435 (UniProt: P15423)
PDBExternal DatabaseDetails
Glu 436-expression tag
Asn 437-expression tag
Leu 438-expression tag
Tyr 439-expression tag
Phe 440-expression tag
Gln 441-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight127684.6
BranchedNumber of molecules3
Total formula weight1597.5
Non-Polymers*Number of molecules1
Total formula weight221.2
All*Total formula weight129503.3
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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