7VM5
Crystal structure of uPA in complex with 4-guanidinobenzoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | U | Urokinase-type plasminogen activator | polymer | 246 | 27715.6 | 1 | UniProt (P00749) Pfam (PF00089) In PDB | Homo sapiens (Human) | uPA |
| 2 | U | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 3 | U | 4-carbamimidamidobenzoic acid | non-polymer | 179.2 | 1 | Chemie (GBS) | |||
| 4 | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
U: 16 - 243 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 122 | Cys 299 | conflict |
| Gln 145 | Asn 322 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27715.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 329.3 | |
| All* | Total formula weight | 28044.9 |
