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7VLN

NSD2-PWWP1 domain bound with an imidazol-5-yl benzonitrile compound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Histone-lysine N-methyltransferase NSD2polymer13215141.53UniProt (O96028)
Pfam (PF00855)
Homo sapiens (human)Multiple myeloma SET domain-containing protein,MMSET,Nuclear SET domain-containing protein 2,Protein trithorax-5,Wolf-Hirschhorn syndrome candidate 1 protein
2D
(B)
4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrilenon-polymer348.41Chemie (7QC)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight45424.5
Non-Polymers*Number of molecules1
Total formula weight348.4
All*Total formula weight45772.9
*Water molecules are not included.

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PDB entries from 2025-07-16

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