7VGE
Structure of the PDZ deleted variant of HtrA2 protease (S306A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Serine protease HTRA2, mitochondrial | polymer | 203 | 21668.6 | 3 | UniProt (O43464) Pfam (PF13365) | Homo sapiens (Human) | High temperature requirement protein A2,HtrA2,Omi stress-regulated endoprotease,Serine protease 25,Serine proteinase OMI |
| 2 | D, F (D, F) | Serine protease HTRA2, mitochondrial | polymer | 202 | 21555.4 | 2 | UniProt (O43464) Pfam (PF13365) | Homo sapiens (Human) | High temperature requirement protein A2,HtrA2,Omi stress-regulated endoprotease,Serine protease 25,Serine proteinase OMI |
| 3 | E (E) | Serine protease HTRA2, mitochondrial | polymer | 201 | 21408.2 | 1 | UniProt (O43464) Pfam (PF13365) | Homo sapiens (Human) | High temperature requirement protein A2,HtrA2,Omi stress-regulated endoprotease,Serine protease 25,Serine proteinase OMI |
Sequence modifications
A, B, C: 140 - 342 (UniProt: O43464)
D, F: 140 - 341 (UniProt: O43464)
E: 140 - 340 (UniProt: O43464)
| PDB | External Database | Details |
|---|---|---|
| Ala 306 | Ser 306 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 306 | Ser 306 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 306 | Ser 306 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 129524.8 | |
| All* | Total formula weight | 129524.8 |
