7VG7

Plexin B1 extracellular fragment in complex with lasso-grafted PB1m6A9 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Plexin-B1	polymer	525	56661.4	1	UniProt (O43157) Pfam (PF01403) Pfam (PF01437) In PDB	Homo sapiens (Human)	Semaphorin receptor SEP
2	B	Uteroglobin,PB1m6A9 peptide,Uteroglobin	polymer	160	18300.0	1	UniProt (P11684) Pfam (PF01099) In PDB	Homo sapiens (Human)	Clara cell phospholipid-binding protein,CCPBP,Clara cells 10 kDa secretory protein,CC10,Secretoglobin family 1A member 1,Urinary protein 1,UP-1,UP1,Urine protein 1
3	A	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5		water	water		18.0	100	Chemie (HOH)

Sequence modifications

A: 19 - 535 (UniProt: O43157)

PDB	External Database	Details
Ser 19	Thr 19	engineered mutation
Thr 536	-	expression tag
Arg 537	-	expression tag
Glu 538	-	expression tag
Asn 539	-	expression tag
Leu 540	-	expression tag
Tyr 541	-	expression tag
Phe 542	-	expression tag
Gln 543	-	expression tag

B: 21 - 89 (UniProt: P11684)

PDB	External Database	Details
Ser 21	Ala 21	engineered mutation

B: 90 - 107 (PDB: 7VG7)
B: 108 - 174 (UniProt: P11684)

PDB	External Database	Details
His 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	74961.4
Non-Polymers*	Number of molecules	2
	Total formula weight	371.4
All*	Total formula weight	75332.8

*Water molecules are not included.