7VFU
Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to ziconotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Voltage-dependent N-type calcium channel subunit alpha-1B | polymer | 2339 | 262831.8 | 1 | UniProt (Q00975) Pfam (PF00520) Pfam (PF08016) Pfam (PF16905) Pfam (PF08763) | Homo sapiens (Human) | Brain calcium channel III,BIII,Calcium channel,L type,alpha-1 polypeptide isoform 5,Voltage-gated calcium channel subunit alpha Cav2.2 |
| 2 | B (E) | Omega-conotoxin MVIIA | polymer | 25 | 2652.2 | 1 | UniProt (P05484) Pfam (PF02950) | Conus magus | SNX-111 |
| 3 | C (D) | Voltage-dependent L-type calcium channel subunit beta-1 | polymer | 598 | 65799.6 | 1 | UniProt (Q02641) Pfam (PF12052) Pfam (PF00625) | Homo sapiens (Human) | CAB1,Calcium channel voltage-dependent subunit beta 1 |
| 4 | D (B) | Voltage-dependent calcium channel subunit alpha-2/delta-1 | polymer | 1103 | 124692.5 | 1 | UniProt (P54289) Pfam (PF00092) Pfam (PF08473) Pfam (PF08399) | Homo sapiens (Human) | Voltage-gated calcium channel subunit alpha-2/delta-1 |
| 5 | E, F (C, F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 6 | G (G) | beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G44266EX) | |||
| 7 | AA, H, I, J, L... (A) | HEXADECANE | non-polymer | 226.4 | 18 | Chemie (R16) | |||
| 8 | BA, K, S (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 3 | Chemie (Y01) | |||
| 9 | CA (A) | [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate | non-polymer | 1047.1 | 1 | Chemie (PT5) | |||
| 10 | DA, EA (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 11 | FA, GA, HA, IA, JA... (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 455976.1 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1759.6 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 8433.0 | |
| All* | Total formula weight | 466168.7 |
