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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7VDV

The overall structure of human chromatin remodeling PBAF-nucleosome complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(B, F)		Histone H4polymer10311394.42UniProt (P62799)
Pfam (PF15511)		Xenopus laevis (African clawed frog)
2B, F
(C, G)		Histone H2Apolymer13014109.42UniProt (Q6AZJ8)
Pfam (PF16211)
Pfam (PF00125)
UniProt (by SIFTS) (P06897)		Xenopus laevis (African clawed frog)
3C, G
(D, H)		Histone H2B 1.1polymer12613965.32UniProt (P02281)
Pfam (PF00125)		Xenopus laevis (African clawed frog)H2B1.1
4D, W
(E, K)		Histone H3polymer13615435.12UniProt (A0A310TTQ1)
Pfam (PF00125)
UniProt (by SIFTS) (P84233)		Xenopus laevis (African clawed frog)
5H
(I)		DNA (207-MER)polymer20763679.61synthetic construct
6I
(J)		DNA (207-MER)polymer20764145.81synthetic construct
7J
(A)		Isoform 2 of Transcription activator BRG1polymer1485169597.91UniProt (P51532)
Pfam (PF08880)
Pfam (PF07529)
Pfam (PF07533)
Pfam (PF00176)
Pfam (PF00271)
Pfam (PF14619)
Pfam (PF00439)		Homo sapiens (Human)ATP-dependent helicase SMARCA4,BRG1-associated factor 190A,BAF190A,Mitotic growth and transcription activator,Protein BRG-1,Protein brahma homolog 1,SNF2-beta,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
8K
(N)		Actin-like protein 6Apolymer42947509.81UniProt (O96019)
Pfam (PF00022)		Homo sapiens (Human)53 kDa BRG1-associated factor A,Actin-related protein Baf53a,ArpNbeta,BRG1-associated factor 53A,BAF53A,INO80 complex subunit K
9L
(P)		Actin, cytoplasmic 1polymer37541782.71UniProt (P60709)
Pfam (PF00022)		Homo sapiens (Human)Beta-actin
10M
(Q)		AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2polymer87097547.11UniProt (Q68CP9)
Pfam (PF01388)
Pfam (PF02257)		Homo sapiens (Human)ARID domain-containing protein 2,BRG1-associated factor 200,BAF200,Zinc finger protein with activation potential,Zipzap/p200,ARID domain-containing protein 2,BRG1-associated factor 200,BAF200,Zinc finger protein with activation potential,Zipzap/p200
11N
(R)		PHD finger protein 10polymer51458254.21UniProt (Q8WUB8)
Pfam (PF00628)		Homo sapiens (Human)BRG1-associated factor 45a,BAF45a,XAP135
12O
(T)		Isoform 2 of Bromodomain-containing protein 7polymer65274385.81UniProt (Q9NPI1)
Pfam (PF00439)
Pfam (PF12024)		Homo sapiens (Human)75 kDa bromodomain protein,Protein CELTIX-1
13P
(U)		unknownpolymer7613.71unidentified
14Q
(V)		SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1polymer38544199.21UniProt (Q12824)
Pfam (PF21459)
Pfam (PF04855)		Homo sapiens (Human)
15R, S
(W, X)		SWI/SNF complex subunit SMARCC2polymer1214133048.12UniProt (Q8TAQ2)
Pfam (PF16496)
Pfam (PF04433)
Pfam (PF00249)
Pfam (PF16498)
Pfam (PF16495)		Homo sapiens (Human)BRG1-associated factor 170,BAF170
16T
(Y)		SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1polymer52960127.31UniProt (Q96GM5)
Pfam (PF02201)		Homo sapiens (Human)60 kDa BRG-1/Brm-associated factor subunit A,BRG1-associated factor 60A,BAF60A,SWI/SNF complex 60 kDa subunit
17U
(Z)		SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1polymer41146710.41UniProt (Q969G3)
Pfam (PF00505)		Homo sapiens (Human)
18V
(a)		Protein polybromo-1polymer1020116762.41UniProt (Q86U86)
Pfam (PF00439)
Pfam (PF01426)
Pfam (PF00505)		Homo sapiens (Human)hPB1,BRG1-associated factor 180,BAF180,Polybromo-1D
19X
(M)		unknownpolymer161379.71unidentified
20Y
(A)		BERYLLIUM TRIFLUORIDE IONnon-polymer66.01Chemie (BEF)
21Z
(A)		MAGNESIUM IONnon-polymer24.31Chemie (MG)
22AA
(A)		ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
Sequence modifications
A: 160 - 1614 (UniProt: P51532)
PDBExternal DatabaseDetails
Met 159-initiating methionine
Ala 1615-expression tag
Ser 1616-expression tag
Gly 1617-expression tag
Gly 1618-expression tag
Ser 1619-expression tag
Trp 1620-expression tag
Ser 1621-expression tag
His 1622-expression tag
Pro 1623-expression tag
Gln 1624-expression tag
Phe 1625-expression tag
Glu 1626-expression tag
Lys 1627-expression tag
Trp 1628-expression tag
Ser 1629-expression tag
His 1630-expression tag
Pro 1631-expression tag
Gln 1632-expression tag
Phe 1633-expression tag
Glu 1634-expression tag
Lys 1635-expression tag
Trp 1636-expression tag
Ser 1637-expression tag
His 1638-expression tag
Pro 1639-expression tag
Gln 1640-expression tag
Phe 1641-expression tag
Glu 1642-expression tag
Lys 1643-expression tag
Q: 1 - 1591 (UniProt: Q68CP9)
Q: 1592 - 1835 (UniProt: Q68CP9)
R: 1 - 498 (UniProt: Q8WUB8)
PDBExternal DatabaseDetails
Met -15-expression tag
His -14-expression tag
His -13-expression tag
His -12-expression tag
His -11-expression tag
His -10-expression tag
His -9-expression tag
His -8-expression tag
His -7-expression tag
His -6-expression tag
His -5-expression tag
His -4-expression tag
His -3-expression tag
Gly -2-expression tag
Glu -1-expression tag
Phe 0-expression tag
Y: 1 - 515 (UniProt: Q96GM5)
PDBExternal DatabaseDetails
Ala 516-expression tag
Ser 517-expression tag
His 518-expression tag
His 519-expression tag
His 520-expression tag
His 521-expression tag
His 522-expression tag
His 523-expression tag
His 524-expression tag
His 525-expression tag
His 526-expression tag
His 527-expression tag
His 528-expression tag
His 529-expression tag
a: 671 - 1689 (UniProt: Q86U86)
PDBExternal DatabaseDetails
Met 670-initiating methionine
-Ala 1444deletion
-Ala 1445deletion
-Gln 1446deletion
-Gln 1447deletion
-Gln 1448deletion
-Gln 1449deletion
-Pro 1450deletion
-Ser 1451deletion
-Ala 1452deletion
-Ser 1453deletion
-Pro 1454deletion
-Arg 1455deletion
-Ala 1456deletion
-Gly 1457deletion
-Thr 1458deletion
-Pro 1459deletion
-Val 1460deletion
-Gly 1461deletion
-Ala 1462deletion
-Leu 1463deletion
-Met 1464deletion
-Gly 1465deletion
-Val 1466deletion
-Val 1467deletion
-Pro 1468deletion
-Pro 1469deletion
-Pro 1470deletion
-Thr 1471deletion
-Pro 1472deletion
-Met 1473deletion
-Gly 1474deletion
-Met 1475deletion
-Leu 1476deletion
-Asn 1477deletion
-Gln 1478deletion
-Gln 1479deletion
-Leu 1480deletion
-Thr 1481deletion
-Pro 1482deletion
-Val 1483deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains24
Total formula weight1262600.4
Non-Polymers*Number of molecules3
Total formula weight517.5
All*Total formula weight1263117.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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