7VDU
The structure of cyclin-dependent kinase 2 (CDK2) in complex with Compound 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cyclin-dependent kinase 2 | polymer | 300 | 34147.6 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (Human) | Cell division protein kinase 2 |
| 2 | A | [1-[3-fluoranyl-4-[(2-piperidin-4-yloxy-1,6-naphthyridin-7-yl)amino]phenyl]pyrazol-3-yl]methanol | non-polymer | 434.5 | 1 | Chemie (65L) | |||
| 3 | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34147.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 434.5 | |
| All* | Total formula weight | 34582.1 |
