7VC2
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L96 and L-proline in space group P21
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Prolyl-tRNA synthetase (ProRS) | polymer | 500 | 57937.3 | 2 | UniProt (A0A7J6JUK2) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) In PDB | Toxoplasma gondii | |
| 2 | A, B | 4-[(3S)-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(5-methoxypyridin-3-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide | non-polymer | 499.5 | 2 | Chemie (1UI) | |||
| 3 | A, B | PROLINE | non-polymer | 115.1 | 2 | Chemie (PRO) | |||
| 4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
| 5 | B | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
A, B: 334 - 830 (UniProt: A0A7J6JUK2)
| PDB | External Database | Details |
|---|---|---|
| Gly 331 | - | expression tag |
| Ala 332 | - | expression tag |
| Met 333 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115874.5 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2009.6 | |
| All* | Total formula weight | 117884.1 |
