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7VB4

A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically dynamic RNA-dependent RNA polymerase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
RNA-directed RNA polymerase nsP4polymer52058392.92UniProt (P03317)
Pfam (PF00978)
Sindbis virus (SINV)Non-structural protein 4,nsP4
2C, D, G, H
(A, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
3E, F, I, J
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
4K, L
(A, B)
waterwater18.0876Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight116785.7
Non-Polymers*Number of molecules8
Total formula weight465.6
All*Total formula weight117251.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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