7V6Y
Cryo-EM structure of Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed with dataset of 7dzq)
Replaces: 7DZQEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein patched homolog 1,Protein patched homolog 1 | polymer | 1090 | 121637.6 | 1 | UniProt (Q61115) Pfam (PF12349) Pfam (PF02460) | Mus musculus (Mouse) | PTC,PTC1,PTC,PTC1 |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C, D (A) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) | |||
| 4 | E (A) | (2S)-2-azanyl-3-[[(2S)-3-butanoyloxy-2-dec-9-enoyloxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid | non-polymer | 481.5 | 1 | Chemie (5VI) | |||
| 5 | F, G, H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A: 2 - 709 (UniProt: Q61115)
A: 710 - 1175 (UniProt: Q61115)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Thr 1176 | - | expression tag |
| Leu 1177 | - | expression tag |
| Glu 1178 | - | expression tag |
| Val 1179 | - | expression tag |
| Leu 1180 | - | expression tag |
| Phe 1181 | - | expression tag |
| Gln 1182 | - | expression tag |
| Gly 1183 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 121637.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1918.4 | |
| All* | Total formula weight | 123980.4 |
