7V6Y

Cryo-EM structure of Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed with dataset of 7dzq)

Replaces:  7DZQ

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008158	molecular_function	hedgehog receptor activity
A	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	PHE87-LEU107
A	VAL1070-PHE1090
A	MET1108-GLY1128
A	VAL1141-LEU1161
A	VAL423-MET443
A	GLY459-ILE479
A	VAL488-PHE508
A	VAL534-PRO554
A	ALA564-MET584
A	ALA735-THR755
A	LEU1014-LEU1034
A	GLY1040-ILE1060

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site_id	SWS_FT_FI2
Number of Residues	605
Details	TOPO_DOM: Extracellular => ECO:0000255

Chain	Residue	Details
A	GLU108-ASP422
A	SER480-GLN487
A	ALA555-ALA563
A	ARG756-TRP1013
A	GLY1061-VAL1069
A	SER1129-ALA1140

---

site_id	SWS_FT_FI3
Number of Residues	207
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	LEU444-ALA458
A	SER509-SER533
A	ASP585-MET829
A	ASN1035-ALA1039
A	LEU1091-HIS1107

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site_id	SWS_FT_FI4
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN127
A	ASN298
A	ASN335
A	ASN400
A	ASN861
A	ASN986

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