7V3B
Crystal structure of NP exonuclease C409A-PCMPS complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nucleoprotein | polymer | 249 | 27661.6 | 2 | UniProt (P13699) Pfam (PF17290) | Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV) | Nucleocapsid protein,Protein N |
| 2 | C, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | PARA-MERCURY-BENZENESULFONIC ACID | non-polymer | 357.8 | 1 | Chemie (PMB) | |||
| 4 | E, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A, B: 342 - 569 (UniProt: P13699)
| PDB | External Database | Details |
|---|---|---|
| Met 321 | - | initiating methionine |
| Gly 322 | - | expression tag |
| Ser 323 | - | expression tag |
| Ser 324 | - | expression tag |
| His 325 | - | expression tag |
| His 326 | - | expression tag |
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| Ser 331 | - | expression tag |
| Ser 332 | - | expression tag |
| Gly 333 | - | expression tag |
| Leu 334 | - | expression tag |
| Val 335 | - | expression tag |
| Pro 336 | - | expression tag |
| Arg 337 | - | expression tag |
| Gly 338 | - | expression tag |
| Ser 339 | - | expression tag |
| His 340 | - | expression tag |
| Met 341 | - | expression tag |
| Ala 409 | Cys 409 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55323.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 537.2 | |
| All* | Total formula weight | 55860.3 |
