7V3B
Crystal structure of NP exonuclease C409A-PCMPS complex
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | ASP389 |
| A | ILE390 |
| A | GLU391 |
| A | HOH703 |
| A | HOH732 |
| A | HOH815 |
| A | HOH819 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue PMB A 602 |
| Chain | Residue |
| A | GLY463 |
| A | SER464 |
| A | ASP465 |
| A | ASP483 |
| A | ILE484 |
| A | ALA485 |
| A | HOH749 |
| A | ARG455 |
| A | CYS461 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 603 |
| Chain | Residue |
| A | GLU399 |
| A | CYS506 |
| A | HIS509 |
| A | CYS529 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 601 |
| Chain | Residue |
| B | ASP389 |
| B | HOH701 |
| B | HOH730 |
| B | HOH786 |
| B | HOH795 |
| B | HOH832 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 602 |
| Chain | Residue |
| B | GLU399 |
| B | CYS506 |
| B | HIS509 |
| B | CYS529 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04085","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21085117","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21262835","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04085","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21085117","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21262835","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22937163","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23615902","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for exonuclease activity","evidences":[{"source":"HAMAP-Rule","id":"MF_04085","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21085117","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
