7V39

Crystal structure of NP exonuclease-PCMB complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Nucleoprotein	polymer	249	27693.6	2	UniProt (P13699) Pfam (PF17290)	Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV)	Nucleocapsid protein,Protein N
2	C, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, F (A, B)	4-(HYDROXYMERCURY)BENZOIC ACID	non-polymer		338.7	2	Chemie (HGB)
4	G, H (A, B)	water	water		18.0	273	Chemie (HOH)

Sequence modifications

A, B: 342 - 569 (UniProt: P13699)

PDB	External Database	Details
Met 321	-	initiating methionine
Gly 322	-	expression tag
Ser 323	-	expression tag
Ser 324	-	expression tag
His 325	-	expression tag
His 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
Ser 331	-	expression tag
Ser 332	-	expression tag
Gly 333	-	expression tag
Leu 334	-	expression tag
Val 335	-	expression tag
Pro 336	-	expression tag
Arg 337	-	expression tag
Gly 338	-	expression tag
Ser 339	-	expression tag
His 340	-	expression tag
Met 341	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55387.3
Non-Polymers*	Number of molecules	4
	Total formula weight	808.2
All*	Total formula weight	56195.5

*Water molecules are not included.