7V2D
Deactive state complex I from Q10 dataset
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 431 | 47265.9 | 1 | UniProt (F1RVN1) Pfam (PF01512) Pfam (PF10589) UniProt (by SIFTS) (A0A4X1SZP7) In PDB | Sus scrofa (pig) | |
| 2 | B | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | polymer | 176 | 20208.0 | 1 | UniProt (A0A287BDC0) Pfam (PF12838) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 23 kDa subunit,Complex I-23kD |
| 3 | C | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7,mitochondrial | polymer | 156 | 17875.0 | 1 | UniProt (I3LK43) Pfam (PF01058) UniProt (by SIFTS) (A0A8D1TL60) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 20 kDa subunit,Complex I-20kD |
| 4 | E | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | polymer | 115 | 13813.0 | 1 | UniProt (A0A480VKQ8) Pfam (PF05347) UniProt (by SIFTS) (F1SJP6) In PDB | Sus scrofa (pig) | |
| 5 | F | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 86 | 9841.3 | 1 | UniProt (F1RGE3) Pfam (PF05047) In PDB | Sus scrofa (pig) | |
| 6 | G, X | Acyl carrier protein, mitochondrial | polymer | 88 | 10133.6 | 2 | UniProt (D0G781) Pfam (PF00550) UniProt (by SIFTS) (A0A287AAR5) In PDB | Sus scrofa (pig) | |
| 7 | H | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | polymer | 112 | 12949.1 | 1 | UniProt (A0A5G2RN85) In PDB | Sus scrofa (pig) | Complex I-13kD-B,NADH-ubiquinone oxidoreductase 13 kDa-B subunit,Complex I subunit B13 |
| 8 | I | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 112 | 12517.4 | 1 | UniProt (A0A4X1VLA2) Pfam (PF07347) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase subunit B14.5a,Complex I-B14.5a |
| 9 | J | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | polymer | 341 | 38840.9 | 1 | UniProt (A0A480QJC4) Pfam (PF01370) UniProt (by SIFTS) (A0A287AE88) In PDB | Sus scrofa (pig) | |
| 10 | K | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | polymer | 42 | 5046.5 | 1 | UniProt (A0A4X1TFI3) Pfam (PF15880) UniProt (by SIFTS) (I3LRR4) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 9 kDa subunit,Complex I-9kD |
| 11 | L | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 125 | 14442.4 | 1 | UniProt (G8IFA6) Pfam (PF04800) UniProt (by SIFTS) (A0A4X1SN37) In PDB | Sus scrofa (pig) | Complex I-18 kDa,NADH-ubiquinone oxidoreductase 18 kDa subunit |
| 12 | M | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 690 | 75770.8 | 1 | UniProt (F1SHD7) Pfam (PF13510) Pfam (PF10588) Pfam (PF00384) Pfam (PF09326) UniProt (by SIFTS) (A0A4X1V1H9) In PDB | Sus scrofa (pig) | |
| 13 | N | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 144 | 17031.2 | 1 | UniProt (F1SQP4) Pfam (PF05071) In PDB | Sus scrofa (pig) | |
| 14 | O | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | polymer | 217 | 23826.3 | 1 | UniProt (A0A287BG40) Pfam (PF01257) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 24 kDa subunit |
| 15 | P | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | polymer | 208 | 24521.7 | 1 | UniProt (A0A286ZNN4) Pfam (PF00329) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 30 kDa subunit,Complex I-30kD |
| 16 | Q | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | polymer | 430 | 49234.3 | 1 | UniProt (A0A480JYS1) Pfam (PF00346) UniProt (by SIFTS) (F1S1A8) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 49 kDa subunit,Complex I-49kD |
| 17 | S | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 70 | 8088.4 | 1 | UniProt (K7GR43) Pfam (PF15879) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase MWFE subunit,Complex I-MWFE |
| 18 | T | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 96 | 10567.6 | 1 | UniProt (F1S031) Pfam (PF10276) In PDB | Sus scrofa (pig) | |
| 19 | U | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | polymer | 83 | 9094.4 | 1 | UniProt (A0A4X1VQ42) Pfam (PF14987) UniProt (by SIFTS) (A0A4X1VPG4) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B9 subunit,Complex I-B9 |
| 20 | V | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 140 | 14555.7 | 1 | UniProt (I3LGM4) Pfam (PF02466) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase subunit B14.7,Complex I-B14.7 |
| 21 | W | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | polymer | 142 | 16709.3 | 1 | UniProt (F1S6Q1) Pfam (PF06212) UniProt (by SIFTS) (A0A8D1NRT6) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B16.6 subunit,Complex I-B16.6 |
| 22 | Y | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial | polymer | 70 | 8430.3 | 1 | UniProt (A0A4X1V766) Pfam (PF14813) UniProt (by SIFTS) (A0A5G2QW32) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase AGGG subunit,Complex I-AGGG |
| 23 | Z | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 84 | 9504.7 | 1 | UniProt (A0A287AS93) Pfam (PF08122) UniProt (by SIFTS) (A0A4X1VD84) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B12 subunit,Complex I-B12 |
| 24 | a | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 140 | 16477.1 | 1 | UniProt (F1SGC6) Pfam (PF09781) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase SGDH subunit,Complex I-SGDH |
| 25 | b | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | polymer | 126 | 15333.8 | 1 | UniProt (Q2EN80) Pfam (PF09782) UniProt (by SIFTS) (A0A480KM09) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B17 subunit,Complex I-B17 |
| 26 | c | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 156 | 18608.8 | 1 | UniProt (F1RWL7) Pfam (PF05821) In PDB | Sus scrofa (pig) | Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit |
| 27 | d | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 175 | 20813.6 | 1 | UniProt (A0A4X1VYV0) Pfam (PF10249) UniProt (by SIFTS) (I3LDC3) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase PDSW subunit,Complex I-PDSW |
| 28 | e | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 107 | 12635.1 | 1 | Pfam (PF10183) UniProt (by SIFTS) (A0A287BMW6) In PDB | Sus scrofa (Pig) | |
| 29 | f | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | polymer | 42 | 4945.7 | 1 | UniProt (A1XQS6) Pfam (PF15088) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase KFYI subunit,Complex I-KFYI |
| 30 | g | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 121 | 14196.5 | 1 | UniProt (A0A480JRW3) Pfam (PF06374) In PDB | Sus scrofa (pig) | |
| 31 | h | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 105 | 12375.4 | 1 | UniProt (F1SV23) Pfam (PF10200) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 15 kDa subunit,Complex I-15 kDa |
| 32 | i | NADH-ubiquinone oxidoreductase chain 2 | polymer | 347 | 39077.5 | 1 | UniProt (O79875) Pfam (PF00361) Pfam (PF06444) In PDB | Sus scrofa (pig) | NADH dehydrogenase subunit 2 |
| 33 | j | NADH-ubiquinone oxidoreductase chain 3 | polymer | 113 | 12798.3 | 1 | UniProt (O79880) Pfam (PF00507) In PDB | Sus scrofa (pig) | NADH dehydrogenase subunit 3 |
| 34 | k | NADH-ubiquinone oxidoreductase chain 4L | polymer | 98 | 10827.3 | 1 | UniProt (P56632) Pfam (PF00420) In PDB | Sus scrofa (pig) | NADH dehydrogenase subunit 4L |
| 35 | l | NADH-ubiquinone oxidoreductase chain 5 | polymer | 603 | 68267.0 | 1 | UniProt (Q71K68) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) UniProt (by SIFTS) (Q9TDR1) In PDB | Sus scrofa (pig) | |
| 36 | m | NADH-ubiquinone oxidoreductase chain 6 | polymer | 175 | 19021.3 | 1 | UniProt (O79882) Pfam (PF00499) In PDB | Sus scrofa (pig) | NADH dehydrogenase subunit 6 |
| 37 | n | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 56 | 6781.9 | 1 | UniProt (F1SD73) Pfam (PF08040) UniProt (by SIFTS) (A0A8D2CGH8) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase MNLL subunit,Complex I-MNLL |
| 38 | o | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | polymer | 128 | 14986.2 | 1 | UniProt (A0A4X1T6M0) Pfam (PF07225) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B15 subunit,Complex I-B15 |
| 39 | p | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 178 | 21733.7 | 1 | UniProt (A0A4X1T0A8) Pfam (PF05347) UniProt (by SIFTS) (K7GSE5) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B22 subunit,Complex I-B22 |
| 40 | r | NADH-ubiquinone oxidoreductase chain 4 | polymer | 459 | 51853.4 | 1 | UniProt (Q7IIB7) Pfam (PF01059) Pfam (PF00361) UniProt (by SIFTS) (O79881) In PDB | Sus scrofa (pig) | |
| 41 | s | NADH-ubiquinone oxidoreductase chain 1 | polymer | 318 | 35667.5 | 1 | UniProt (O79874) Pfam (PF00146) In PDB | Sus scrofa (pig) | NADH dehydrogenase subunit 1 |
| 42 | u | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 171 | 19932.9 | 1 | UniProt (F1SLR1) Pfam (PF06747) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 19 kDa subunit,Complex I-19kD |
| 43 | v | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 131 | 15954.3 | 1 | UniProt (F1SCH1) Pfam (PF05676) In PDB | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B18 subunit,Complex I-B18 |
| 44 | w | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 320 | 36792.7 | 1 | UniProt (F1SIS9) Pfam (PF01712) In PDB | Sus scrofa (pig) | |
| 45 | M, A, B, C | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 46 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 47 | V, b, i, j, l... | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 9 | Chemie (PEE) | |||
| 48 | r, g, j, C | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL | non-polymer | 767.1 | 6 | Chemie (PLX) | |||
| 49 | G, X | S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate | non-polymer | 540.7 | 2 | Chemie (8Q1) | |||
| 50 | J | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 51 | M, O | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 52 | M | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 53 | r, u, N, V, a... | CARDIOLIPIN | non-polymer | 1464.0 | 9 | Chemie (CDL) | |||
| 54 | T | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 55 | s | Coenzyme Q10, (2Z,6E,10Z,14E,18E,22E,26Z)-isomer | non-polymer | 863.3 | 1 | Chemie (UQ) | |||
| 56 | w | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
v: 2 - 131 (UniProt: F1SCH1)
| PDB | External Database | Details |
|---|---|---|
| Myr 1 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 45 |
| Total formula weight | 949481.1 | |
| Non-Polymers* | Number of molecules | 40 |
| Total formula weight | 30600.3 | |
| All* | Total formula weight | 980081.4 |
