7UYW
Crystal structure of JAK2 kinase domain in complex with compound 30
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase JAK2 | polymer | 291 | 34366.2 | 1 | UniProt (O60674) Pfam (PF07714) | Homo sapiens (human) | Janus kinase 2,JAK-2 |
| 2 | B (A) | 2-(2,6-difluorophenyl)-4-[4-(pyrrolidine-1-carbonyl)anilino]-5H-pyrrolo[3,4-b]pyridin-5-one | non-polymer | 432.4 | 1 | Chemie (OV0) | |||
| 3 | C (A) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34366.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 432.4 | |
| All* | Total formula weight | 34798.6 |
