7UXP

Structure of PDL1 in complex with FP28132, a Helicon Polypeptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Programmed cell death 1 ligand 1	polymer	129	14810.0	2	UniProt (Q9NZQ7) Pfam (PF07686)	Homo sapiens (human)	hPD-L1,B7 homolog 1,B7-H1
2	C, D (C, D)	FP28132	polymer	18	2015.2	2		synthetic construct
3	E, G (C, D)	AMINO GROUP	non-polymer		16.0	2	Chemie (NH2)
4	F, H (C, D)	N,N'-(1,4-phenylene)diacetamide	non-polymer		192.2	2	Chemie (WHL)
5	I, J, K (A, B, D)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, B: 18 - 134 (UniProt: Q9NZQ7)

PDB	External Database	Details
Met 17	-	initiating methionine
Ala 135	-	expression tag
Ala 136	-	expression tag
Ala 137	-	expression tag
Leu 138	-	expression tag
Glu 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	33650.4
Non-Polymers*	Number of molecules	4
	Total formula weight	416.5
All*	Total formula weight	34066.9

*Water molecules are not included.