Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

7UX4

Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from Thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network.

Replaces:  7JNS
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Secondary-alcohol dehydrogenasepolymer35237652.81UniProt (P14941)
Pfam (PF08240)
Pfam (PF00107)
UniProt (by SIFTS) (B0KBL1)
Thermoanaerobacter pseudethanolicus
2B, C, D
(B, C, D)
NADP-dependent isopropanol dehydrogenasepolymer35237680.83UniProt (P14941)
Pfam (PF08240)
Pfam (PF00107)
UniProt (by SIFTS) (B0KBL1)
Thermoanaerobacter pseudethanolicus
3E, K, Q, U
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
4F, L, R, V
(A, B, C, D)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.44Chemie (NAP)
5G, J, M, P, S...
(A, B, C, D)
POTASSIUM IONnon-polymer39.18Chemie (K)
6H, N, X
(A, B, D)
(1S,3S)-3-methylcyclohexan-1-olnon-polymer114.23Chemie (NWO)
7I, O
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
8AA, BA, CA, Z
(B, C, D, A)
waterwater18.0313Chemie (HOH)
Sequence modifications
A: 1 - 352 (UniProt: P14941)
PDBExternal DatabaseDetails
Ala 86Ile 86engineered mutation
B, C, D: 1 - 352 (UniProt: P14941)
PDBExternal DatabaseDetails
Ala 86Ile 86conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight150695.2
Non-Polymers*Number of molecules21
Total formula weight3961.5
All*Total formula weight154656.7
*Water molecules are not included.

230083

数据于2025-01-15公开中

PDB statisticsPDBj update infoContact PDBjnumon