7UX4

Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from Thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network.

Replaces:  7JNS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008270	molecular_function	zinc ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0008270	molecular_function	zinc ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0008270	molecular_function	zinc ion binding
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0008270	molecular_function	zinc ion binding
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00059
Number of Residues	15
Details	ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEaVGEvvevGseV

Chain	Residue	Details
A	GLY58-VAL72
B	GLY58-VAL72

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	BINDING: BINDING => ECO:0000269|PubMed:20102159, ECO:0000269|PubMed:9836873

Chain	Residue	Details
B	CYS37
B	HIS59
B	ASP150
C	CYS37
C	HIS59
C	ASP150
D	CYS37
D	HIS59
D	ASP150

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site_id	SWS_FT_FI2
Number of Residues	15
Details	BINDING: BINDING => ECO:0000269|PubMed:9836873

Chain	Residue	Details
B	ILE175
C	LYS340
D	ILE175
D	GLY198
D	TYR218
D	VAL265
D	LYS340
B	GLY198
B	TYR218
B	VAL265
B	LYS340
C	ILE175
C	GLY198
C	TYR218
C	VAL265

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