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7UW2

Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with UAB116 and coactivator peptide GRIP-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARetinoic acid receptor RXR-alphapolymer24026856.01UniProt (P19793)
Pfam (PF00104)
In PDB
Homo sapiens (human)Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha
2BNuclear receptor coactivator 2polymer131579.91UniProt (Q15596)
In PDB
Homo sapiensNCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2
3A(2E,4E,6Z,8E)-8-{3-[(2S)-butan-2-yl]-2-(3-methylbutyl)cyclohex-2-en-1-ylidene}-3,7-dimethylocta-2,4,6-trienoic acidnon-polymer370.61Chemie (OI2)
4waterwater18.0102Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28435.9
Non-Polymers*Number of molecules1
Total formula weight370.6
All*Total formula weight28806.5
*Water molecules are not included.

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PDB entries from 2024-07-24

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