7UW0
Crystal structure of human ClpP protease in complex with TR-133
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | ATP-dependent Clp protease proteolytic subunit, mitochondrial | polymer | 221 | 24179.9 | 7 | UniProt (Q16740) Pfam (PF00574) In PDB | Homo sapiens (human) | Endopeptidase Clp |
| 2 | A, B, C, D, E... | 3-({3-[(4-bromophenyl)methyl]-4-oxo-3,5,7,8-tetrahydropyrido[4,3-d]pyrimidin-6(4H)-yl}methyl)benzonitrile | non-polymer | 435.3 | 7 | Chemie (P4I) | |||
| 3 | water | water | 18.0 | 70 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G: 58 - 277 (UniProt: Q16740)
| PDB | External Database | Details |
|---|---|---|
| Ser 57 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 169259.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 3047.2 | |
| All* | Total formula weight | 172306.3 |
