7UVJ
Rationally Designed ED1 Epitope-Scaffold Immunogen for SARS-CoV-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Apolipoprotein E | polymer | 147 | 16957.2 | 2 | UniProt (P02649) Pfam (PF01442) | Escherichia coli | Apo-E, ED1 |
| 2 | C, F (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | D, G (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 4 | E (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 282 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 166 (UniProt: P02649)
| PDB | External Database | Details |
|---|---|---|
| Gly 20 | - | expression tag |
| His 21 | - | expression tag |
| Met 22 | - | expression tag |
| Lys 132 | Glu 149 | conflict |
| Asn 136 | Val 153 | conflict |
| Gly 143 | Arg 160 | conflict |
| Gln 146 | Arg 163 | conflict |
| Asp 147 | Lys 164 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33914.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 455.5 | |
| All* | Total formula weight | 34369.9 |
