7UUU
First bromodomain of BRDT liganded with compound 2c
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain testis-specific protein | polymer | 113 | 13319.4 | 1 | UniProt (Q58F21) Pfam (PF00439) | Homo sapiens (human) | Cancer/testis antigen 9,CT9,RING3-like protein |
| 2 | B (A) | prop-2-en-1-yl (5S)-1-ethyl-7-methyl-5-(4-methylphenyl)-2,4-dioxo-1,2,3,4,5,8-hexahydropyrido[2,3-d]pyrimidine-6-carboxylate | non-polymer | 381.4 | 1 | Chemie (OFR) | |||
| 3 | C, D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | G (A) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A: 29 - 137 (UniProt: Q58F21)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Ala 26 | - | expression tag |
| Ala 27 | - | expression tag |
| Ser 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13319.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 629.7 | |
| All* | Total formula weight | 13949.1 |
