7UUO
Crystal structure of aminoglycoside resistance enzyme ApmA H135A mutant, complex with tobramycin and coenzyme A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Aminocyclitol acetyltransferase ApmA | polymer | 276 | 31257.3 | 3 | UniProt (A0A1D0AST6) | Staphylococcus aureus | |
| 2 | D, F, H (A, B, C) | TOBRAMYCIN | non-polymer | 467.5 | 3 | Chemie (TOY) | |||
| 3 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | G (B) | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
| 5 | I, J, K (A, B, C) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 274 (UniProt: A0A1D0AST6)
| PDB | External Database | Details |
|---|---|---|
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ala 135 | His 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 93771.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2232.1 | |
| All* | Total formula weight | 96003.9 |
