7UT5

Acinetobacter baumannii dihydroorotate dehydrogenase bound with inhibitor DSM186

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dihydroorotate dehydrogenase (quinone)	polymer	354	38299.9	2	UniProt (B7GZW7) Pfam (PF01180)	Acinetobacter baumannii	DHOdehase,DHOD,DHODase,Dihydroorotate oxidase
2	C, I (A, B)	(4R)-7-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl]imidazo[1,2-a]pyrimidin-5-amine	non-polymer		350.3	2	Chemie (OBR)
3	D, J (A, B)	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	2	Chemie (FMN)
4	E, K (A, B)	OROTIC ACID	non-polymer		156.1	2	Chemie (ORO)
5	F, G, H (A)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
6	L, M (A, B)	water	water		18.0	413	Chemie (HOH)

Sequence modifications

A, B: 1 - 334 (UniProt: B7GZW7)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76599.9
Non-Polymers*	Number of molecules	9
	Total formula weight	2201.8
All*	Total formula weight	78801.7

*Water molecules are not included.