7UT5

Acinetobacter baumannii dihydroorotate dehydrogenase bound with inhibitor DSM186

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004152	molecular_function	dihydroorotate dehydrogenase activity
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0006222	biological_process	UMP biosynthetic process
A	0009220	biological_process	pyrimidine ribonucleotide biosynthetic process
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
A	0044205	biological_process	'de novo' UMP biosynthetic process
A	0106430	molecular_function	dihydroorotate dehydrogenase (quinone) activity
B	0004152	molecular_function	dihydroorotate dehydrogenase activity
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0006222	biological_process	UMP biosynthetic process
B	0009220	biological_process	pyrimidine ribonucleotide biosynthetic process
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
B	0044205	biological_process	'de novo' UMP biosynthetic process
B	0106430	molecular_function	dihydroorotate dehydrogenase (quinone) activity

Functional Information from PROSITE/UniProt

site_id	PS00911
Number of Residues	20
Details	DHODEHASE_1 Dihydroorotate dehydrogenase signature 1. GfieiGTITprpQsGNpkPR

Chain	Residue	Details
A	GLY77-ARG96

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site_id	PS00912
Number of Residues	21
Details	DHODEHASE_2 Dihydroorotate dehydrogenase signature 2. LIGvGGIlSgeqAaaKQqAGA

Chain	Residue	Details
A	LEU289-ALA309

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00225

Chain	Residue	Details
A	SER172
B	SER172

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site_id	SWS_FT_FI2
Number of Residues	26
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00225

Chain	Residue	Details
A	ALA59
A	LYS63
A	THR83
A	ASN108
A	ASN136
A	ASN169
A	ASN174
A	LYS214
A	THR242
A	ASN243
A	GLY265
A	GLY294
A	TYR315
B	ALA59
B	LYS63
B	THR83
B	ASN108
B	ASN136
B	ASN169
B	ASN174
B	LYS214
B	THR242
B	ASN243
B	GLY265
B	GLY294
B	TYR315

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