7UQ3

JmjC domain-containing protein 5 (JMJD5) in complex with Mn and (S)-2-(1-hydroxy-2,5-dioxopyrrolidin-3-yl)acetic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Bifunctional peptidase and arginyl-hydroxylase JMJD5	polymer	256	29733.5	1	UniProt (Q8N371) Pfam (PF13621) In PDB	Homo sapiens (human)	JmjC domain-containing protein 5,Jumonji C domain-containing protein 5,L-arginine (3R)-hydroxylase KDM8
2	A	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
3	A	[(3S)-1-hydroxy-2,5-dioxopyrrolidin-3-yl]acetic acid	non-polymer		173.1	1	Chemie (O2U)
4	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5		water	water		18.0	290	Chemie (HOH)

Sequence modifications

A: 183 - 416 (UniProt: Q8N371)

PDB	External Database	Details
Met 161	-	initiating methionine
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
Ser 168	-	expression tag
Ser 169	-	expression tag
Gly 170	-	expression tag
Val 171	-	expression tag
Asp 172	-	expression tag
Leu 173	-	expression tag
Gly 174	-	expression tag
Thr 175	-	expression tag
Glu 176	-	expression tag
Asn 177	-	expression tag
Leu 178	-	expression tag
Tyr 179	-	expression tag
Phe 180	-	expression tag
Gln 181	-	expression tag
Ser 182	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29733.5
Non-Polymers*	Number of molecules	4
	Total formula weight	412.2
All*	Total formula weight	30145.8

*Water molecules are not included.