7UQ3
JmjC domain-containing protein 5 (JMJD5) in complex with Mn and (S)-2-(1-hydroxy-2,5-dioxopyrrolidin-3-yl)acetic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bifunctional peptidase and arginyl-hydroxylase JMJD5 | polymer | 256 | 29733.5 | 1 | UniProt (Q8N371) Pfam (PF13621) | Homo sapiens (human) | JmjC domain-containing protein 5,Jumonji C domain-containing protein 5,L-arginine (3R)-hydroxylase KDM8 |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (A) | [(3S)-1-hydroxy-2,5-dioxopyrrolidin-3-yl]acetic acid | non-polymer | 173.1 | 1 | Chemie (O2U) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F (A) | water | water | 18.0 | 290 | Chemie (HOH) |
Sequence modifications
A: 183 - 416 (UniProt: Q8N371)
| PDB | External Database | Details |
|---|---|---|
| Met 161 | - | initiating methionine |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| His 165 | - | expression tag |
| His 166 | - | expression tag |
| His 167 | - | expression tag |
| Ser 168 | - | expression tag |
| Ser 169 | - | expression tag |
| Gly 170 | - | expression tag |
| Val 171 | - | expression tag |
| Asp 172 | - | expression tag |
| Leu 173 | - | expression tag |
| Gly 174 | - | expression tag |
| Thr 175 | - | expression tag |
| Glu 176 | - | expression tag |
| Asn 177 | - | expression tag |
| Leu 178 | - | expression tag |
| Tyr 179 | - | expression tag |
| Phe 180 | - | expression tag |
| Gln 181 | - | expression tag |
| Ser 182 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29733.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 412.2 | |
| All* | Total formula weight | 30145.8 |
