7UPX
Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Spike glycoprotein | polymer | 1310 | 144858.0 | 1 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus | S glycoprotein,E2,Peplomer protein |
2 | H | SP1-77 Fab heavy chain | polymer | 451 | 49665.7 | 1 | Homo sapiens (Human) | ||
3 | L | SP1-77 Fab light chain | polymer | 213 | 23294.6 | 1 | Homo sapiens (Human) | ||
4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) |
Sequence modifications
A: 1 - 1273 (UniProt: P0DTC2)
H: 1 - 94 (PDB: 7UPX)
H: 95 - 102 (PDB: 7UPX)
H: 103 - 440 (PDB: 7UPX)
L: 1 - 97 (PDB: 7UPX)
L: 98 - 108 (PDB: 7UPX)
L: 109 - 214 (PDB: 7UPX)
PDB | External Database | Details |
---|---|---|
Gly 614 | Asp 614 | engineered mutation |
Leu 1274 | - | expression tag |
Glu 1275 | - | expression tag |
Ser 1276 | - | expression tag |
Gly 1277 | - | expression tag |
Gly 1278 | - | expression tag |
Gly 1279 | - | expression tag |
Ser 1280 | - | expression tag |
Ala 1281 | - | expression tag |
Trp 1282 | - | expression tag |
Ser 1283 | - | expression tag |
His 1284 | - | expression tag |
Pro 1285 | - | expression tag |
Gln 1286 | - | expression tag |
Phe 1287 | - | expression tag |
Glu 1288 | - | expression tag |
Lys 1289 | - | expression tag |
Gly 1290 | - | expression tag |
Gly 1291 | - | expression tag |
Gly 1292 | - | expression tag |
Ser 1293 | - | expression tag |
Gly 1294 | - | expression tag |
Gly 1295 | - | expression tag |
Gly 1296 | - | expression tag |
Ser 1297 | - | expression tag |
Gly 1298 | - | expression tag |
Gly 1299 | - | expression tag |
Ser 1300 | - | expression tag |
Ser 1301 | - | expression tag |
Ala 1302 | - | expression tag |
Trp 1303 | - | expression tag |
Ser 1304 | - | expression tag |
His 1305 | - | expression tag |
Pro 1306 | - | expression tag |
Gln 1307 | - | expression tag |
Phe 1308 | - | expression tag |
Glu 1309 | - | expression tag |
Lys 1310 | - | expression tag |
H: 95 - 102 (PDB: 7UPX)
H: 103 - 440 (PDB: 7UPX)
L: 1 - 97 (PDB: 7UPX)
L: 98 - 108 (PDB: 7UPX)
L: 109 - 214 (PDB: 7UPX)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 217818.4 | |
Branched | Number of molecules | 1 |
Total formula weight | 570.5 | |
All* | Total formula weight | 218388.9 |