7UOV
Native Lassa glycoprotein in complex with neutralizing antibodies 12.1F and 37.2D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G, M (H, D, F) | 12.1F heavy chain (variable domain) | polymer | 114 | 12731.2 | 3 | Homo sapiens | ||
| 2 | B, H, N (L, E, G) | 12.1F light chain (variable domain) | polymer | 106 | 11602.9 | 3 | Homo sapiens | ||
| 3 | C, I, O (A, B, C) | Glycoprotein G1 | polymer | 259 | 29064.4 | 3 | UniProt (P08669) Pfam (PF00798) | Lassa virus | |
| 4 | D, J, P (a, b, c) | Glycoprotein G2 | polymer | 232 | 26798.0 | 3 | UniProt (P08669) Pfam (PF00798) | Lassa virus | GP2 |
| 5 | E, K, Q (T, P, R) | 37.2D light chain (variable domain) | polymer | 105 | 11412.5 | 3 | Homo sapiens | ||
| 6 | F, L, R (S, O, Q) | 37.2D heavy chain (variable domain) | polymer | 126 | 13946.5 | 3 | Homo sapiens | ||
| 7 | FA, GA, OA, S, SA... (f, g, o, I, s...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G15407YE) | |||
| 8 | CA, JA, PA, T, UA... (Z, j, p, J, u...) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 6 | In PDB GlyTouCan (G56014GC) | |||
| 9 | NA, U (n, K) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 2 | In PDB GlyTouCan (G42466VF) | |||
| 10 | AA, DA, EA, LA, RA... (X, d, e, l, r...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 7 | In PDB GlyTouCan (G32152BH) | |||
| 11 | HA, IA, KA, QA, TA... (h, i, k, q, t...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 8 | In PDB GlyTouCan (G42666HT) | |||
| 12 | BA, MA, XA (Y, m, x) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 3 | In PDB GlyTouCan (G82348BZ) | |||
| 13 | YA (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
a, b, c: 260 - 491 (UniProt: P08669)
| PDB | External Database | Details |
|---|---|---|
| Thr 332 | Met 332 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 316666.4 | |
| Branched | Number of molecules | 32 |
| Total formula weight | 23441.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 340329.1 |
