7UOS
Structure of WNK1 inhibitor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase WNK1 | polymer | 290 | 33454.5 | 1 | UniProt (Q9JIH7) Pfam (PF00069) In PDB | Rattus norvegicus (Norway rat) | Protein kinase lysine-deficient 1,Protein kinase with no lysine 1 |
| 2 | A | 4-[bromo(dichloro)methanesulfonyl]-N-cyclohexyl-2-nitroaniline | non-polymer | 446.1 | 1 | Chemie (WIB) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A: 194 - 483 (UniProt: Q9JIH7)
| PDB | External Database | Details |
|---|---|---|
| Ser 198 | Asn 198 | conflict |
| Ala 382 | Ser 382 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33454.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 570.3 | |
| All* | Total formula weight | 34024.7 |
