7UMS

Structure of the VP5/VP8 assembly from the human rotavirus strain CDC-9 in complex with antibody 41 - Upright conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (T, U, V)	Outer capsid protein VP8*	polymer	230	26248.8	3	UniProt (X4YMN0) Pfam (PF00426)	Rotavirus
2	B, D, F (1, 2, 3)	Outer capsid protein VP5*	polymer	529	59605.3	3	UniProt (X4YMN0) Pfam (PF17477) Pfam (PF17478)	Rotavirus
3	G, I (4, 6)	Fab 41 heavy chain	polymer	236	25386.3	2		Homo sapiens
4	H, J (5, 7)	Fab 41 light chain	polymer	217	23322.6	2		Homo sapiens
5	AA, BA, K, L, M... (A, B, C, D, E...)	Intermediate capsid protein VP6	polymer	397	44995.0	18	UniProt (A0A223GHC7) Pfam (PF00980)	Rotavirus
6	CA, DA, EA, FA, GA... (a, b, c, d, e...)	Outer capsid glycoprotein VP7	polymer	326	37435.9	18	UniProt (B1NP55) Pfam (PF00434)	Rotavirus
7	UA (S)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
8	AB, AC, BB, BC, CD... (b, f, k, o, g...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	35	Chemie (NAG)
9	AD, AE, BD, BE, CB... (j, o, b, f, k...)	CALCIUM ION	non-polymer		40.1	72	Chemie (CA)

Sequence modifications

T, U, V: 1 - 230 (UniProt: X4YMN0)

PDB	External Database	Details
Gly 28	Glu 28	conflict
Asp 51	Gly 51	conflict

1, 2, 3: 247 - 775 (UniProt: X4YMN0)

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R: 1 - 397 (UniProt: A0A223GHC7)

PDB	External Database	Details
Val 281	Ile 281	conflict

a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r: 1 - 326 (UniProt: B1NP55)

PDB	External Database	Details
Ile 108	Thr 108	conflict
Ser 147	Asn 147	conflict

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.