7UKV
Wild type EGFR in complex with Lazertinib (YH25448)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 328 | 37391.2 | 1 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
| 2 | B (A) | N-[5-{[(4P)-4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl]amino}-4-methoxy-2-(morpholin-4-yl)phenyl]propanamide | non-polymer | 556.7 | 1 | Chemie (ZRT) | |||
| 3 | C (A) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37391.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 556.7 | |
| All* | Total formula weight | 37947.9 |
