7UJN

Structure of Human SAMHD1 with Non-Hydrolysable dGTP Analog

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	polymer	626	72305.4	4	UniProt (Q9Y3Z3) Pfam (PF07647) Pfam (PF01966)	Homo sapiens (human)	dNTPase,Dendritic cell-derived IFNG-induced protein,DCIP,Monocyte protein 5,MOP-5,SAM domain and HD domain-containing protein 1,hSAMHD1
2	E, F, G, H, I... (A, B, C, D)	2'-deoxyguanosine-5'-O-(1-thiotriphosphate)	non-polymer		523.2	12	Chemie (T8T)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	289221.7
Non-Polymers*	Number of molecules	12
	Total formula weight	6279.0
All*	Total formula weight	295500.6

*Water molecules are not included.