7UI7

CryoEM structure of LARGE1 from C2 reconstruction

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Xylosyl- and glucuronyltransferase LARGE1	polymer	770	89806.2	2	UniProt (O95461) Pfam (PF01501) Pfam (PF13896)	Homo sapiens (human)	Acetylglucosaminyltransferase-like 1A,Glycosyltransferase-like protein,LARGE xylosyl- and glucuronyltransferase 1
2	C, D, E, F (A, B)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)

Sequence modifications

A, B: 34 - 756 (UniProt: O95461)

PDB	External Database	Details
Met -7	-	initiating methionine
Ser -6	-	expression tag
Ala -5	-	expression tag
Leu -4	-	expression tag
Leu -3	-	expression tag
Ile -2	-	expression tag
Leu -1	-	expression tag
Ala 0	-	expression tag
Leu 1	-	expression tag
Val 2	-	expression tag
Gly 3	-	expression tag
Ala 4	-	expression tag
Ala 5	-	expression tag
Val 6	-	expression tag
Ala 7	-	expression tag
Asp 8	-	expression tag
Tyr 9	-	expression tag
Lys 10	-	expression tag
Asp 11	-	expression tag
His 12	-	expression tag
Asp 13	-	expression tag
Gly 14	-	expression tag
Asp 15	-	expression tag
Tyr 16	-	expression tag
Lys 17	-	expression tag
Asp 18	-	expression tag
His 19	-	expression tag
Asp 20	-	expression tag
Ile 21	-	expression tag
Asp 22	-	expression tag
Tyr 23	-	expression tag
Lys 24	-	expression tag
Asp 25	-	expression tag
Asp 26	-	expression tag
Asp 27	-	expression tag
Asp 28	-	expression tag
Lys 29	-	expression tag
Leu 30	-	expression tag
Ala 31	-	expression tag
Ala 32	-	expression tag
Ala 33	-	expression tag
His 757	-	expression tag
His 758	-	expression tag
His 759	-	expression tag
His 760	-	expression tag
His 761	-	expression tag
His 762	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	179612.5
Non-Polymers*	Number of molecules	4
	Total formula weight	219.8
All*	Total formula weight	179832.2

*Water molecules are not included.