7UI7

CryoEM structure of LARGE1 from C2 reconstruction

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0003824	molecular_function	catalytic activity
A	0005794	cellular_component	Golgi apparatus
A	0005886	cellular_component	plasma membrane
A	0006044	biological_process	N-acetylglucosamine metabolic process
A	0006486	biological_process	obsolete protein glycosylation
A	0006493	biological_process	protein O-linked glycosylation
A	0006688	biological_process	glycosphingolipid biosynthetic process
A	0008375	molecular_function	acetylglucosaminyltransferase activity
A	0009101	biological_process	glycoprotein biosynthetic process
A	0010656	biological_process	negative regulation of muscle cell apoptotic process
A	0015020	molecular_function	glucuronosyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0016758	molecular_function	hexosyltransferase activity
A	0030145	molecular_function	manganese ion binding
A	0031594	cellular_component	neuromuscular junction
A	0032991	cellular_component	protein-containing complex
A	0035022	biological_process	positive regulation of Rac protein signal transduction
A	0035252	molecular_function	UDP-xylosyltransferase activity
A	0035269	biological_process	protein O-linked glycosylation via mannose
A	0042285	molecular_function	xylosyltransferase activity
A	0043403	biological_process	skeletal muscle tissue regeneration
A	0046716	biological_process	muscle cell cellular homeostasis
A	0046872	molecular_function	metal ion binding
A	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0060538	biological_process	skeletal muscle organ development
A	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering
B	0000139	cellular_component	Golgi membrane
B	0003824	molecular_function	catalytic activity
B	0005794	cellular_component	Golgi apparatus
B	0005886	cellular_component	plasma membrane
B	0006044	biological_process	N-acetylglucosamine metabolic process
B	0006486	biological_process	obsolete protein glycosylation
B	0006493	biological_process	protein O-linked glycosylation
B	0006688	biological_process	glycosphingolipid biosynthetic process
B	0008375	molecular_function	acetylglucosaminyltransferase activity
B	0009101	biological_process	glycoprotein biosynthetic process
B	0010656	biological_process	negative regulation of muscle cell apoptotic process
B	0015020	molecular_function	glucuronosyltransferase activity
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0016758	molecular_function	hexosyltransferase activity
B	0030145	molecular_function	manganese ion binding
B	0031594	cellular_component	neuromuscular junction
B	0032991	cellular_component	protein-containing complex
B	0035022	biological_process	positive regulation of Rac protein signal transduction
B	0035252	molecular_function	UDP-xylosyltransferase activity
B	0035269	biological_process	protein O-linked glycosylation via mannose
B	0042285	molecular_function	xylosyltransferase activity
B	0043403	biological_process	skeletal muscle tissue regeneration
B	0046716	biological_process	muscle cell cellular homeostasis
B	0046872	molecular_function	metal ion binding
B	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
B	0060538	biological_process	skeletal muscle organ development
B	1904395	biological_process	positive regulation of skeletal muscle acetylcholine-gated channel clustering

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	550
Details	Region: {"description":"Xylosyltransferase activity","evidences":[{"source":"PubMed","id":"22223806","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25138275","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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