7UDS
Structure of lineage I (Pinneo) Lassa virus glycoprotein bound to Fab 25.10C
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D, F, H | 25.10C Fab Heavy Chain | polymer | 226 | 24270.3 | 3 | Homo sapiens | ||
2 | L, G, E | 25.10C Fab Light Chain | polymer | 209 | 22812.4 | 3 | Homo sapiens | ||
3 | A, C, B | Glycoprotein G1 | polymer | 258 | 28987.4 | 3 | UniProt (Q9IMJ0) Pfam (PF00798) In PDB | Lassa mammarenavirus | |
4 | a, c, b | Glycoprotein G2 | polymer | 206 | 23348.1 | 3 | UniProt (Q9IMJ0) Pfam (PF00798) In PDB | Lassa mammarenavirus | |
5 | I, O, T | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
6 | J, M, N, P, R... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 8 | In PDB GlyTouCan (G42666HT) | |||
7 | K, Q, V | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
8 | A, C, B, a, c... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) |
Sequence modifications
A, C, B: 1 - 258 (UniProt: Q9IMJ0)
a, c, b: 259 - 418 (UniProt: Q9IMJ0)
PDB | External Database | Details |
---|---|---|
Cys 206 | Lys 206 | engineered mutation |
Arg 257 | Leu 257 | engineered mutation |
Arg 258 | Leu 258 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Pro 328 | Glu 328 | engineered mutation |
Cys 359 | Gly 359 | engineered mutation |
Leu 419 | - | expression tag |
Pro 420 | - | expression tag |
Glu 421 | - | expression tag |
Thr 422 | - | expression tag |
Gly 423 | - | expression tag |
Leu 424 | - | expression tag |
Val 425 | - | expression tag |
Asp 426 | - | expression tag |
Leu 427 | - | expression tag |
Glu 428 | - | expression tag |
Val 429 | - | expression tag |
Asp 430 | - | expression tag |
Asp 431 | - | expression tag |
Asp 432 | - | expression tag |
Asp 433 | - | expression tag |
Lys 434 | - | expression tag |
Ala 435 | - | expression tag |
Gly 436 | - | expression tag |
Trp 437 | - | expression tag |
Ser 438 | - | expression tag |
His 439 | - | expression tag |
Pro 440 | - | expression tag |
Gln 441 | - | expression tag |
Phe 442 | - | expression tag |
Glu 443 | - | expression tag |
Lys 444 | - | expression tag |
Gly 445 | - | expression tag |
Gly 446 | - | expression tag |
Gly 447 | - | expression tag |
Ser 448 | - | expression tag |
Gly 449 | - | expression tag |
Gly 450 | - | expression tag |
Gly 451 | - | expression tag |
Ser 452 | - | expression tag |
Gly 453 | - | expression tag |
Gly 454 | - | expression tag |
Gly 455 | - | expression tag |
Ser 456 | - | expression tag |
Trp 457 | - | expression tag |
Ser 458 | - | expression tag |
His 459 | - | expression tag |
Pro 460 | - | expression tag |
Gln 461 | - | expression tag |
Phe 462 | - | expression tag |
Glu 463 | - | expression tag |
Lys 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 298254.5 | |
Branched | Number of molecules | 14 |
Total formula weight | 8373.7 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 2212.1 | |
All* | Total formula weight | 308840.3 |