7UDG
Integrin alpha IIB beta3 complex with lotrafiban
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Integrin alpha-IIb heavy chain | polymer | 457 | 49516.0 | 2 | UniProt (P08514) Pfam (PF01839) | Homo sapiens (human) | |
| 2 | B, D (B, D) | Isoform Beta-3C of Integrin beta-3 | polymer | 472 | 52087.9 | 2 | UniProt (P05106) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) | Homo sapiens (human) | Platelet membrane glycoprotein IIIa,GPIIIa |
| 3 | E, G (E, H) | 10E5 Fab heavy chain | polymer | 221 | 23766.5 | 2 | Mus musculus (mouse) | ||
| 4 | F, H (F, L) | 10E5 Fab light chain | polymer | 214 | 23332.7 | 2 | Mus musculus (mouse) | ||
| 5 | I (G) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 6 | J, L (I, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 7 | K (J) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 8 | AA, HA, M, N, NA... (C, A, L) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 9 | DA, EA, FA, GA, JA... (C, D, A, B) | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
| 10 | IA, U (D, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 11 | KA, W (D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 12 | MA, X (D, B) | Lotrafiban | non-polymer | 428.5 | 2 | Chemie (MWI) | |||
| 13 | BA, CA, LA (C, D) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 14 | OA, PA, QA, RA, SA... (A, B, C, D, E...) | water | water | 18.0 | 688 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 297406.1 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2508.3 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 2719.8 | |
| All* | Total formula weight | 302634.1 |
