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7UBR

Integrin alpha IIB beta3 complex with GR144053

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Integrin alpha-IIbpolymer45449228.62UniProt (P08514)
Pfam (PF01839)
Homo sapiens (human)GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb
2B, D
(B, D)
Isoform Beta-3C of Integrin beta-3polymer47252087.92UniProt (P05106)
Pfam (PF17205)
Pfam (PF00362)
Pfam (PF18372)
Homo sapiens (human)Platelet membrane glycoprotein IIIa,GPIIIa
3E, G
(E, H)
10E5 Fab heavy chainpolymer22123766.52Homo sapiens (human)
4F, H
(F, L)
10E5 Fab light chainpolymer21423332.72Homo sapiens (human)
5I
(G)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G22768VO)
6J, L
(I, K)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
7K
(J)
alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G81315DD)
8AA, BA, CA, DA, JA...
(B, C, A, D, L)
SULFATE IONnon-polymer96.112Chemie (SO4)
9FA, GA, HA, IA, O...
(C, A)
CALCIUM IONnon-polymer40.18Chemie (CA)
10KA, LA, MA, V, W...
(D, B)
MANGANESE (II) IONnon-polymer54.96Chemie (MN)
11NA, Y
(D, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
12PA, Z
(D, B)
{4-[4-(4-carbamimidoylphenyl)piperazin-1-yl]piperidin-1-yl}acetic acidnon-polymer345.42Chemie (MJX)
13EA, OA
(C, D)
CHLORIDE IONnon-polymer35.52Chemie (CL)
14SA, TA, UA, VA, WA...
(A, B, C, D, E...)
waterwater18.01183Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight296831.4
BranchedNumber of molecules4
Total formula weight2508.3
Non-Polymers*Number of molecules32
Total formula weight3007.2
All*Total formula weight302346.9
*Water molecules are not included.

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PDB entries from 2024-10-30

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