7U8E

Crystal structure of antibody Ab246 in complex with SARS-CoV-2 receptor binding domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	205	23073.8	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
2	H	Antibody Ab246 Fab heavy chain	polymer	227	24152.1	1		Homo sapiens (Human)
3	L	Antibody Ab246 Fab light chain	polymer	221	23628.3	1		Homo sapiens (Human)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	A, H, L	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
6	H	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7		water	water		18.0	200	Chemie (HOH)

Sequence modifications

A: 331 - 527 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 528	-	expression tag
Ser 529	-	expression tag
His 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70854.2
Non-Polymers*	Number of molecules	8
	Total formula weight	809.2
All*	Total formula weight	71663.4

*Water molecules are not included.